Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM52006
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase.
IC50
24082±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | metallo-beta-lactamase IMP-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27125.88
Organism:
Pseudomonas aeruginosa
Description:
gi_27368096
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM52006
Synonyms:
2-(2-aminocarbonylsulfanylethanoylamino)benzoic acid | 2-[(2-carbamoylsulfanylacetyl)amino]benzoic acid | 2-[[2-(carbamoylthio)-1-oxoethyl]amino]benzoic acid | 2-[[2-(carbamoylthio)acetyl]amino]benzoic acid | MLS000737416 | SMR000528134 | cid_224665
Type:
Small organic molecule
Emp. Form.:
C10H10N2O4S
Mol. Mass.:
254.262
SMILES:
NC(=O)SCC(=O)Nc1ccccc1C(O)=O
Structure:
Search PDB for entries with ligand similarity: