Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52499
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52499
Synonyms:
2-[5-(4-cyanobenzylidene)-3-[2-(2-furfurylamino)-2-keto-ethyl]-4-keto-thiazolidin-2-ylidene]acetic acid ethyl ester | 2-[5-[(4-cyanophenyl)methylidene]-3-[2-(2-furanylmethylamino)-2-oxoethyl]-4-oxo-2-thiazolidinylidene]acetic acid ethyl ester | MLS000334515 | SMR000249273 | cid_4875598 | ethyl 2-[5-[(4-cyanophenyl)methylidene]-3-[2-(furan-2-ylmethylamino)-2-oxidanylidene-ethyl]-4-oxidanylidene-1,3-thiazolidin-2-ylidene]ethanoate | ethyl 2-[5-[(4-cyanophenyl)methylidene]-3-[2-(furan-2-ylmethylamino)-2-oxoethyl]-4-oxo-1,3-thiazolidin-2-ylidene]acetate
Type:
Small organic molecule
Emp. Form.:
C22H19N3O5S
Mol. Mass.:
437.468
SMILES:
CCOC(=O)C=c1sc(=Cc2ccc(cc2)C#N)c(=O)n1CC(=O)NCc1ccco1
Structure:
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