Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52799
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52799
Synonyms:
MLS000332913 | N-(4-{[1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-2,4,6-trioxo-tetrahydro-pyrimidin-(5E)-ylidenemethyl]-amino}-p henyl)-acetamide | N-[4-[[(E)-(1-homoveratryl-2,4,6-triketo-hexahydropyrimidin-5-ylidene)methyl]amino]phenyl]acetamide | N-[4-[[(E)-[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4,6-trioxo-1,3-diazinan-5-ylidene]methyl]amino]phenyl]acetamide | N-[4-[[(E)-[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methyl]amino]phenyl]ethanamide | SMR000436229 | cid_5517961
Type:
Small organic molecule
Emp. Form.:
C23H24N4O6
Mol. Mass.:
452.4599
SMILES:
COc1ccc(CCN2C(=O)NC(=O)C(=CNc3ccc(NC(C)=O)cc3)C2=O)cc1OC |w:15.15|
Structure:
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