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Target
M1 family aminopeptidase
Ligand
BDBM53655
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP)
IC50
8180±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP) PubChem Bioassay (2008)[AID] 
Target
Name:
M1 family aminopeptidase
Synonyms:
AMPN_PLAF7 | M1AAP | Zinc aminopeptidase | m1-family aminopeptidase
Type:
PROTEIN
Mol. Mass.:
126072.31
Organism:
Plasmodium falciparum (isolate FcB1 / Columbia)
Description:
ChEMBL_735637
Residue:
1085
Sequence:
MKLTKGCAYKYIIFTVLILANILYDNKKRCMIKKNLRISSCGIISRLLKSNSNYNSFNKNYNFTSAISELQFSNFWNLDILQKDIFSNIHNNKNKPQSYIIHKRLMSEKGDNNNNNHQNNNGNDNKKRLGSVVNNEENTCSDKRMKPFEEGHGITQVDKMNNNSDHLQQNGVMNLNSNNVENNNNNNSVVVKKNEPKIHYRKDYKPSGFIINNVTLNINIHDNETIVRSVLDMDISKHNVGEDLVFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGLINPENGKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDNLTDEERILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFNLTPVNAQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKEYIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFELYDKTYKLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPNDIRAVYLPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFKLWNKLDTKRQELMLNEMNTMLQEPNISNNLKEYLLRLTNKL
  
Inhibitor
Name:
BDBM53655
Synonyms:
1-[1-(2,3-Dihydro-benzo[1,4]dioxine-6-sulfonyl)-piperidin-4-yl]-5-fluoro-1H-benzotriazole | 1-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidinyl]-5-fluorobenzotriazole | 1-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidyl]-5-fluoro-benzotriazole | 1-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperidin-4-yl]-5-fluoranyl-benzotriazole | 1-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperidin-4-yl]-5-fluorobenzotriazole | MLS000074693 | SMR000006510 | cid_651033
Type:
Small organic molecule
Emp. Form.:
C19H19FN4O4S
Mol. Mass.:
418.442
SMILES:
Fc1ccc2n(nnc2c1)C1CCN(CC1)S(=O)(=O)c1ccc2OCCOc2c1
Structure:
Search PDB for entries with ligand similarity: