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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46191
Substrate
n/a
Meas. Tech.
MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50
949±n/a nM
Citation
 PubChem, PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46191
Synonyms:
1-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-(4-chlorophenyl)urea | 1-[2,3-bis(2-furyl)quinoxalin-6-yl]-3-(4-chlorophenyl)urea | 1-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-(4-chlorophenyl)urea | MLS-0292127.0001 | cid_24178225
Type:
Small organic molecule
Emp. Form.:
C23H15ClN4O3
Mol. Mass.:
430.843
SMILES:
Clc1ccc(NC(=O)Nc2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: