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Target
Bcl-2-like protein 2
Ligand
BDBM33104
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W
EC50
21240±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W PubChem Bioassay (2009)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33104
Synonyms:
(E)-3-[5-(2-nitrophenyl)-2-furanyl]-1-phenyl-2-propen-1-one | (E)-3-[5-(2-nitrophenyl)-2-furyl]-1-phenyl-prop-2-en-1-one | (E)-3-[5-(2-nitrophenyl)furan-2-yl]-1-phenyl-prop-2-en-1-one | (E)-3-[5-(2-nitrophenyl)furan-2-yl]-1-phenylprop-2-en-1-one | 3-[5-(2-Nitro-phenyl)-furan-2-yl]-1-phenyl-propenone | MLS000553332 | SMR000175498 | cid_5334380
Type:
Small organic molecule
Emp. Form.:
C19H13NO4
Mol. Mass.:
319.3108
SMILES:
[O-][N+](=O)c1ccccc1-c1ccc(\C=C\C(=O)c2ccccc2)o1
Structure:
Search PDB for entries with ligand similarity: