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Target
Bcl-2-like protein 2
Ligand
BDBM54716
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W
EC50
23050±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W PubChem Bioassay (2009)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM54716
Synonyms:
(4-chloro-2,5-dimethoxy-phenyl)-(4-chlorodithiazolidin-5-ylidene)amine | 4-chloranyl-N-(4-chloranyl-2,5-dimethoxy-phenyl)-1,2,3-dithiazolidin-5-imine | 4-chloro-N-(4-chloro-2,5-dimethoxyphenyl)-5-dithiazolidinimine | 4-chloro-N-(4-chloro-2,5-dimethoxyphenyl)dithiazolidin-5-imine | UNM-0000306190 | cid_44203218
Type:
Small organic molecule
Emp. Form.:
C10H10Cl2N2O2S2
Mol. Mass.:
325.235
SMILES:
COc1cc(\N=C2/SSNC2Cl)c(OC)cc1Cl
Structure:
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