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Target
Bcl-2-like protein 2
Ligand
BDBM33087
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W
EC50
11410±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W PubChem Bioassay (2009)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33087
Synonyms:
2,3-bis(2-furanyl)-N-(phenylmethyl)-6-quinoxalinecarboxamide | 2,3-bis(furan-2-yl)-N-(phenylmethyl)quinoxaline-6-carboxamide | MLS000534716 | N-benzyl-2,3-bis(2-furyl)quinoxaline-6-carboxamide | N-benzyl-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | N-benzyl-2,3-di-2-furyl-6-quinoxalinecarboxamide | SMR000142133 | cid_1329592
Type:
Small organic molecule
Emp. Form.:
C24H17N3O3
Mol. Mass.:
395.4101
SMILES:
O=C(NCc1ccccc1)c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: