Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM33075
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM33075
Synonyms:
2,3-bis(2-furanyl)-N-[3-(trifluoromethyl)phenyl]-6-quinoxalinecarboxamide | 2,3-bis(2-furyl)-N-[3-(trifluoromethyl)phenyl]quinoxaline-6-carboxamide | 2,3-bis(furan-2-yl)-N-[3-(trifluoromethyl)phenyl]quinoxaline-6-carboxamide | 2,3-di-2-furyl-N-[3-(trifluoromethyl)phenyl]-6-quinoxalinecarboxamide | MLS000534761 | SMR000142217 | cid_1331611
Type:
Small organic molecule
Emp. Form.:
C24H14F3N3O3
Mol. Mass.:
449.3815
SMILES:
FC(F)(F)c1cccc(NC(=O)c2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)c1
Structure:
Search PDB for entries with ligand similarity: