Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM54972
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM54972
Synonyms:
(4Z)-4-[4-(2,4-dinitrophenoxy)-3-methoxy-benzylidene]-5-methyl-2-phenyl-2-pyrazolin-3-one | (4Z)-4-[[4-(2,4-dinitrophenoxy)-3-methoxy-phenyl]methylidene]-5-methyl-2-phenyl-pyrazol-3-one | (4Z)-4-[[4-(2,4-dinitrophenoxy)-3-methoxyphenyl]methylidene]-5-methyl-2-phenyl-3-pyrazolone | (4Z)-4-[[4-(2,4-dinitrophenoxy)-3-methoxyphenyl]methylidene]-5-methyl-2-phenylpyrazol-3-one | 4-[4-(2,4-Dinitro-phenoxy)-3-methoxy-benzylidene]-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one | MLS000561792 | SMR000175653 | cid_5758789
Type:
Small organic molecule
Emp. Form.:
C24H18N4O7
Mol. Mass.:
474.4223
SMILES:
COc1cc([CH+]c2c(C)[n-]n(-c3ccccc3)c2=O)ccc1Oc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O
Structure:
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