Reaction Details Report a problem with these data
Target
Guanyl-specific ribonuclease T1
Ligand
BDBM55010
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
IC50
>55688±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay (2009)[AID] 
Target
Name:
Guanyl-specific ribonuclease T1
Synonyms:
RNT1_ASPOR | rntA | unnamed protein product
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13952.57
Organism:
Aspergillus oryzae
Description:
gi_83774548
Residue:
130
Sequence:
MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVGSNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFVECT
  
Inhibitor
Name:
BDBM55010
Synonyms:
1-methyl-6-oxidanylidene-N'-[(Z)-(2-oxidanylidenenaphthalen-1-ylidene)methyl]pyridine-3-carbohydrazide | 1-methyl-6-oxo-N'-[(Z)-(2-oxo-1-naphthalenylidene)methyl]-3-pyridinecarbohydrazide | 1-methyl-6-oxo-N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-3-carbohydrazide | 6-keto-N'-[(Z)-(2-keto-1-naphthylidene)methyl]-1-methyl-nicotinohydrazide | MLS000714412 | SMR000274391 | cid_5334123
Type:
Small organic molecule
Emp. Form.:
C18H15N3O3
Mol. Mass.:
321.33
SMILES:
Cn1cc(ccc1=O)C(=O)NN=Cc1c(O)ccc2ccccc12 |w:11.11|
Structure:
Search PDB for entries with ligand similarity: