Reaction Details Report a problem with these data
Target
Streptokinase A
Ligand
BDBM56880
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56880
Synonyms:
(4-Methyl-5-pyrazin-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetic acid methyl ester | 2-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)thio]acetic acid methyl ester | 2-[[4-methyl-5-(2-pyrazinyl)-1,2,4-triazol-3-yl]thio]acetic acid methyl ester | MLS000074748 | SMR000007641 | cid_645359 | methyl 2-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetate | methyl 2-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethanoate
Type:
Small organic molecule
Emp. Form.:
C10H11N5O2S
Mol. Mass.:
265.292
SMILES:
COC(=O)CSc1nnc(-c2cnccn2)n1C
Structure:
Search PDB for entries with ligand similarity: