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Target
Streptokinase A
Ligand
BDBM56881
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
13048±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56881
Synonyms:
MLS000074270 | N-(2-Azepan-1-yl-phenyl)-2-(3,4-dihydro-1H-isoquinolin-2-yl)-acetamide | N-[2-(1-azepanyl)phenyl]-2-(3,4-dihydro-1H-isoquinolin-2-yl)acetamide;oxalic acid | N-[2-(azepan-1-yl)phenyl]-2-(3,4-dihydro-1H-isoquinolin-2-yl)acetamide;oxalic acid | N-[2-(azepan-1-yl)phenyl]-2-(3,4-dihydro-1H-isoquinolin-2-yl)ethanamide;ethanedioic acid | SMR000007580 | cid_645470
Type:
Small organic molecule
Emp. Form.:
C23H29N3O
Mol. Mass.:
363.4959
SMILES:
O=C(CN1CCc2ccccc2C1)Nc1ccccc1N1CCCCCC1
Structure:
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