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Target
Streptokinase A
Ligand
BDBM56884
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56884
Synonyms:
3-(4-Butyl-3,5-dimethyl-pyrazol-1-yl)-5-ethyl-5H-[1,2,4]triazino[5,6-b]indole | 3-(4-butyl-3,5-dimethyl-1-pyrazolyl)-5-ethyl-[1,2,4]triazino[5,6-b]indole | 3-(4-butyl-3,5-dimethyl-pyrazol-1-yl)-5-ethyl-[1,2,4]triazin[5,6-b]indole | 3-(4-butyl-3,5-dimethyl-pyrazol-1-yl)-5-ethyl-[1,2,4]triazino[5,6-b]indole | 3-(4-butyl-3,5-dimethylpyrazol-1-yl)-5-ethyl-[1,2,4]triazino[5,6-b]indole | MLS000073008 | SMR000001269 | cid_646211
Type:
Small organic molecule
Emp. Form.:
C20H24N6
Mol. Mass.:
348.4448
SMILES:
CCCCc1c(C)nn(c1C)-c1nnc2c3ccccc3n(CC)c2n1
Structure:
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