Reaction Details Report a problem with these data
Target
Streptokinase A
Ligand
BDBM47396
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
63702±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM47396
Synonyms:
(5-hydroxynaphthalen-1-yl) benzoate | (5-oxidanylnaphthalen-1-yl) benzoate | Benzoic acid 5-hydroxy-naphthalen-1-yl ester | MLS000030944 | SMR000009914 | benzoic acid (5-hydroxy-1-naphthalenyl) ester | benzoic acid (5-hydroxy-1-naphthyl) ester | cid_646429
Type:
Small organic molecule
Emp. Form.:
C17H12O3
Mol. Mass.:
264.2754
SMILES:
Oc1cccc2c(OC(=O)c3ccccc3)cccc12
Structure:
Search PDB for entries with ligand similarity: