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Target
Streptokinase A
Ligand
BDBM56886
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56886
Synonyms:
Furan-2-carboxylic acid [1-(2-phenoxy-ethyl)-1H-benzoimidazol-2-yl]-amide | MLS000072184 | N-[1-(2-phenoxyethyl)-2-benzimidazolyl]-2-furancarboxamide | N-[1-(2-phenoxyethyl)benzimidazol-2-yl]-2-furamide | N-[1-(2-phenoxyethyl)benzimidazol-2-yl]furan-2-carboxamide | SMR000012916 | cid_646847
Type:
Small organic molecule
Emp. Form.:
C20H17N3O3
Mol. Mass.:
347.3673
SMILES:
O=C(Nc1nc2ccccc2n1CCOc1ccccc1)c1ccco1
Structure:
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