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Target
Streptokinase A
Ligand
BDBM39425
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM39425
Synonyms:
6-(4-Diethylamino-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione | 6-[4-(diethylamino)phenyl]-1,3-dimethyl-pyrrolo[3,4-d]pyrimidine-2,4-dione | 6-[4-(diethylamino)phenyl]-1,3-dimethyl-pyrrolo[3,4-d]pyrimidine-2,4-quinone | 6-[4-(diethylamino)phenyl]-1,3-dimethylpyrrolo[3,4-d]pyrimidine-2,4-dione | MLS000033618 | SMR000013755 | cid_648214
Type:
Small organic molecule
Emp. Form.:
C18H22N4O2
Mol. Mass.:
326.3929
SMILES:
CCN(CC)c1ccc(cc1)-n1cc2n(C)c(=O)n(C)c(=O)c2c1
Structure:
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