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Target
Streptokinase A
Ligand
BDBM56897
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56897
Synonyms:
MLS000071820 | N-[2-(4-Methoxy-phenyl)-6-methyl-2H-benzotriazol-5-yl]-isobutyramide | N-[2-(4-methoxyphenyl)-6-methyl-5-benzotriazolyl]-2-methylpropanamide | N-[2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-yl]-2-methyl-propanamide | N-[2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-yl]-2-methyl-propionamide | N-[2-(4-methoxyphenyl)-6-methylbenzotriazol-5-yl]-2-methylpropanamide | SMR000011222 | cid_651820
Type:
Small organic molecule
Emp. Form.:
C18H20N4O2
Mol. Mass.:
324.377
SMILES:
COc1ccc(cc1)-n1nc2cc(C)c(NC(=O)C(C)C)cc2n1
Structure:
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