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Target
Streptokinase A
Ligand
BDBM50244355
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM50244355
Synonyms:
(2S,3R)-2-amino-1,3-octadecanediol | (2S,3R)-2-aminooctadecane-1,3-diol | (R-(R*,S*))-2-aminooctadecane-1,3-diol | C18-dihydrosphingosine | CHEMBL448741 | D-erythro-1,3-dihydroxy-2-aminooctadecane | D-erythro-2-amino-1,3-octadecanediol | D-erythro-C18-dihydrosphingosine | Safingol | cid_3126 | octadecasphinganine | sphinganine
Type:
Small organic molecule
Emp. Form.:
C18H39NO2
Mol. Mass.:
301.5078
SMILES:
CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO |r|
Structure:
Search PDB for entries with ligand similarity: