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Target
Streptokinase A
Ligand
BDBM56911
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56911
Synonyms:
2-(1-methyl-6-oxidanyl-4-oxidanylidene-pyrimidin-2-yl)sulfanyl-N-naphthalen-1-yl-ethanamide | 2-(6-hydroxy-1-methyl-4-oxopyrimidin-2-yl)sulfanyl-N-naphthalen-1-ylacetamide | 2-[(6-hydroxy-1-methyl-4-oxo-2-pyrimidinyl)thio]-N-(1-naphthalenyl)acetamide | 2-[(6-hydroxy-4-keto-1-methyl-pyrimidin-2-yl)thio]-N-(1-naphthyl)acetamide | MLS000078330 | SMR000039918 | cid_658924
Type:
Small organic molecule
Emp. Form.:
C17H15N3O3S
Mol. Mass.:
341.384
SMILES:
Cn1c(SCC(=O)Nc2cccc3ccccc23)nc(O)cc1=O
Structure:
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