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Target
Streptokinase A
Ligand
BDBM39861
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM39861
Synonyms:
Cyclopropanecarboxylic acid [1,4]dioxan-2-ylmethyl-(6-ethoxy-2-oxo-1,2-dihydro-quinolin-3-ylmethyl)-amide | MLS000031787 | N-(1,4-dioxan-2-ylmethyl)-N-[(6-ethoxy-2-keto-1H-quinolin-3-yl)methyl]cyclopropanecarboxamide | N-(1,4-dioxan-2-ylmethyl)-N-[(6-ethoxy-2-oxidanylidene-1H-quinolin-3-yl)methyl]cyclopropanecarboxamide | N-(1,4-dioxan-2-ylmethyl)-N-[(6-ethoxy-2-oxo-1H-quinolin-3-yl)methyl]cyclopropanecarboxamide | SMR000005826 | cid_655565
Type:
Small organic molecule
Emp. Form.:
C21H26N2O5
Mol. Mass.:
386.4415
SMILES:
CCOc1ccc2[nH]c(=O)c(CN(CC3COCCO3)C(=O)C3CC3)cc2c1
Structure:
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