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Target
Streptokinase A
Ligand
BDBM52093
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
26167±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM52093
Synonyms:
2-cyano-N-cyclohexyl-2-[3-(4-methyl-1-piperidinyl)-2-quinoxalinyl]acetamide | 2-cyano-N-cyclohexyl-2-[3-(4-methylpiperidin-1-yl)quinoxalin-2-yl]acetamide | 2-cyano-N-cyclohexyl-2-[3-(4-methylpiperidin-1-yl)quinoxalin-2-yl]ethanamide | 2-cyano-N-cyclohexyl-2-[3-(4-methylpiperidino)quinoxalin-2-yl]acetamide | MLS000079934 | SMR000040612 | cid_659494
Type:
Small organic molecule
Emp. Form.:
C23H29N5O
Mol. Mass.:
391.5093
SMILES:
CC1CCN(CC1)c1nc2ccccc2nc1C(C#N)C(=O)NC1CCCCC1
Structure:
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