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Target
Streptokinase A
Ligand
BDBM54885
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
8536±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54885
Synonyms:
BRD-K67237401-001-04-0 | N,N-diethylcarbamodithioic acid [2-[(4,5-diphenyl-2-oxazolyl)amino]-2-oxoethyl] ester | N,N-diethylcarbamodithioic acid [2-[(4,5-diphenyloxazol-2-yl)amino]-2-keto-ethyl] ester | [2-[(4,5-diphenyl-1,3-oxazol-2-yl)amino]-2-oxidanylidene-ethyl] N,N-diethylcarbamodithioate | [2-[(4,5-diphenyl-1,3-oxazol-2-yl)amino]-2-oxoethyl] N,N-diethylcarbamodithioate | cid_1968717
Type:
Small organic molecule
Emp. Form.:
C22H23N3O2S2
Mol. Mass.:
425.567
SMILES:
CCN(CC)C(=S)SCC(=O)Nc1nc(c(o1)-c1ccccc1)-c1ccccc1
Structure:
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