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Target
Streptokinase A
Ligand
BDBM55028
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
2231±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM55028
Synonyms:
MLS000587332 | N-(4-keto-6,6-dimethyl-2-nonyl-5,8-dihydropyrano[2,3]thieno[2,4-d]pyrimidin-3-yl)-2-nitro-benzamide | N-(6,6-Dimethyl-2-nonyl-4-oxo-5,8-dihydro-4H,6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-3-yl)-2-nitro-benzamide | N-(6,6-dimethyl-2-nonyl-4-oxidanylidene-5,8-dihydropyrano[2,3]thieno[2,4-d]pyrimidin-3-yl)-2-nitro-benzamide | N-(6,6-dimethyl-2-nonyl-4-oxo-5,8-dihydropyrano[2,3]thieno[2,4-d]pyrimidin-3-yl)-2-nitrobenzamide | SMR000211350 | cid_1601813
Type:
Small organic molecule
Emp. Form.:
C27H34N4O5S
Mol. Mass.:
526.648
SMILES:
CCCCCCCCCc1nc2sc3COC(C)(C)Cc3c2c(=O)n1NC(=O)c1ccccc1[N+]([O-])=O
Structure:
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