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Target
G-protein coupled receptor 35
Ligand
BDBM41526
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
1313.309±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM41526
Synonyms:
MLS000581136 | N-(3-chloranyl-4-methyl-phenyl)-2-[1-[(4-ethoxyphenyl)amino]-1-oxidanylidene-propan-2-yl]oxy-benzamide | N-(3-chloro-4-methyl-phenyl)-2-[2-keto-1-methyl-2-(p-phenetidino)ethoxy]benzamide | N-(3-chloro-4-methylphenyl)-2-[1-(4-ethoxyanilino)-1-oxopropan-2-yl]oxybenzamide | N-(3-chloro-4-methylphenyl)-2-{2-[(4-ethoxyphenyl)amino]-1-methyl-2-oxoethoxy}benzamide | SMR000200375 | cid_2961024
Type:
Small organic molecule
Emp. Form.:
C25H25ClN2O4
Mol. Mass.:
452.93
SMILES:
CCOc1ccc(NC(=O)C(C)Oc2ccccc2C(=O)Nc2ccc(C)c(Cl)c2)cc1
Structure:
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