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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50258439
Substrate
n/a
Meas. Tech.
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay
EC50
6040±n/a nM
Citation
 PubChem, PC Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50258439
Synonyms:
1-(4-bromobenzyl)indoline-2,3-dione | CHEMBL523685 | CVD-0005886 | LOR-NEU-c8f11034-5 | VU0119498 | cid_3008304
Type:
Small organic molecule
Emp. Form.:
C15H10BrNO2
Mol. Mass.:
316.149
SMILES:
Brc1ccc(CN2C(=O)C(=O)c3ccccc23)cc1
Structure:
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