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Target
Neuropeptide Y receptor type 2
Ligand
BDBM61794
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
13745±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61794
Synonyms:
3-[(2-amino-5-bromo-3-pyridinyl)sulfonylamino]-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]propanamide | 3-[(2-amino-5-bromo-3-pyridyl)sulfonylamino]-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]propionamide | 3-[(2-amino-5-bromopyridin-3-yl)sulfonylamino]-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)propanamide | 3-[(2-azanyl-5-bromanyl-pyridin-3-yl)sulfonylamino]-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)propanamide | MLS000094435 | N~3~-[(2-amino-5-bromopyridin-3-yl)sulfonyl]-N~1~-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-beta-alaninamide | SMR000030006 | cid_3235884
Type:
Small organic molecule
Emp. Form.:
C12H15BrN6O3S3
Mol. Mass.:
467.385
SMILES:
CCSc1nnc(NC(=O)CCNS(=O)(=O)c2cc(Br)cnc2N)s1
Structure:
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