Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM61797
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
13753±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61797
Synonyms:
MLS000046894 | N-(2-cyclohex-1-en-1-ylethyl)-6-[(diethylamino)sulfonyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide | N-[2-(1-cyclohexenyl)ethyl]-6-(diethylsulfamoyl)-4-oxo-1H-quinoline-3-carboxamide | N-[2-(cyclohexen-1-yl)ethyl]-6-(diethylsulfamoyl)-4-keto-1H-quinoline-3-carboxamide | N-[2-(cyclohexen-1-yl)ethyl]-6-(diethylsulfamoyl)-4-oxidanylidene-1H-quinoline-3-carboxamide | N-[2-(cyclohexen-1-yl)ethyl]-6-(diethylsulfamoyl)-4-oxo-1H-quinoline-3-carboxamide | SMR000032905 | cid_3244114
Type:
Small organic molecule
Emp. Form.:
C22H29N3O4S
Mol. Mass.:
431.548
SMILES:
CCN(CC)S(=O)(=O)c1ccc2ncc(C(=O)NCCC3=CCCCC3)c(O)c2c1 |t:20|
Structure:
Search PDB for entries with ligand similarity: