Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM34406
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM34406
Synonyms:
4-(5-methyl-7-oxo-2-sulfanylidene-4H-thiazolo[4,5-d]pyrimidin-3-yl)benzoic acid ethyl ester | 4-(7-keto-5-methyl-2-thioxo-4H-thiazolo[4,5-d]pyrimidin-3-yl)benzoic acid ethyl ester | MLS000044856 | SMR000022966 | cid_3245713 | ethyl 4-(5-methyl-7-oxidanylidene-2-sulfanylidene-4H-[1,3]thiazolo[4,5-d]pyrimidin-3-yl)benzoate | ethyl 4-(5-methyl-7-oxo-2-sulfanylidene-4H-[1,3]thiazolo[4,5-d]pyrimidin-3-yl)benzoate | ethyl 4-(5-methyl-7-oxo-2-thioxo-6,7-dihydro[1,3]thiazolo[4,5-d]pyrimidin-3(2H)-yl)benzoate
Type:
Small organic molecule
Emp. Form.:
C15H13N3O3S2
Mol. Mass.:
347.412
SMILES:
CCOC(=O)c1ccc(cc1)-n1c2nc(C)[nH]c(=O)c2sc1=S
Structure:
Search PDB for entries with ligand similarity: