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Target
Neuropeptide Y receptor type 2
Ligand
BDBM61819
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61819
Synonyms:
6-(2,3-dihydro-1H-indol-1-ylsulfonyl)-N-(3-methoxypropyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide | 6-(2,3-dihydroindol-1-ylsulfonyl)-N-(3-methoxypropyl)-4-oxidanylidene-1H-quinoline-3-carboxamide | 6-(2,3-dihydroindol-1-ylsulfonyl)-N-(3-methoxypropyl)-4-oxo-1H-quinoline-3-carboxamide | 6-indolin-1-ylsulfonyl-4-keto-N-(3-methoxypropyl)-1H-quinoline-3-carboxamide | MLS000673772 | SMR000315013 | cid_3635312
Type:
Small organic molecule
Emp. Form.:
C22H23N3O5S
Mol. Mass.:
441.5
SMILES:
COCCCNC(=O)c1cnc2ccc(cc2c1O)S(=O)(=O)N1CCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: