Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM62191
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM62191
Synonyms:
MLS-0071544.0001 | N-[4-(4-benzylpiperazine-1-carbonyl)benzyl]benzenesulfonamide | N-[[4-(4-benzylpiperazine-1-carbonyl)phenyl]methyl]benzenesulfonamide | N-[[4-[4-(phenylmethyl)piperazin-1-yl]carbonylphenyl]methyl]benzenesulfonamide | N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide | cid_9550286
Type:
Small organic molecule
Emp. Form.:
C25H27N3O3S
Mol. Mass.:
449.565
SMILES:
O=C(N1CCN(Cc2ccccc2)CC1)c1ccc(CNS(=O)(=O)c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: