Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM40197
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM40197
Synonyms:
(2Z)-2-[(8-quinolinylamino)methylidene]-1-benzothiophen-3-one | (2Z)-2-[(8-quinolylamino)methylene]benzothiophen-3-one | (2Z)-2-[(quinolin-8-ylamino)methylidene]-1-benzothiophen-3-one | 2-[(8-quinolinylamino)methylene]-1-benzothiophen-3(2H)-one | MLS000530291 | SMR000135268 | cid_5407397
Type:
Small organic molecule
Emp. Form.:
C18H12N2OS
Mol. Mass.:
304.366
SMILES:
Oc1c(C=Nc2cccc3cccnc23)sc2ccccc12 |w:4.4|
Structure:
Search PDB for entries with ligand similarity: