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Target
Delta-type opioid receptor
Ligand
BDBM47164
Substrate
n/a
Meas. Tech.
HTS Image-Based Screen for Antagonists of the DOR Receptor
IC50
10299±n/a nM
Citation
 PubChem, PC HTS Image-Based Screen for Antagonists of the DOR Receptor PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM47164
Synonyms:
(4,5-dibromo-6-oxopyridazin-1-yl)methyl 4-fluorobenzoate | 4-fluorobenzoic acid (4,5-dibromo-6-keto-pyridazin-1-yl)methyl ester | 4-fluorobenzoic acid (4,5-dibromo-6-oxo-1-pyridazinyl)methyl ester | MLS000541288 | SMR000126146 | [4,5-bis(bromanyl)-6-oxidanylidene-pyridazin-1-yl]methyl 4-fluoranylbenzoate | [4,5-dibromo-6-oxo-1(6H)-pyridazinyl]methyl 4-fluorobenzenecarboxylate | cid_1474489
Type:
Small organic molecule
Emp. Form.:
C12H7Br2FN2O3
Mol. Mass.:
406.002
SMILES:
Fc1ccc(cc1)C(=O)OCn1ncc(Br)c(Br)c1=O
Structure:
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