Reaction Details Report a problem with these data
Target
Epstein-Barr nuclear antigen 1
Ligand
BDBM57703
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
IC50
2733±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay (2010)[AID] 
Target
Name:
Epstein-Barr nuclear antigen 1
Synonyms:
EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56444.81
Organism:
Human herpesvirus 4
Description:
gi_23893623
Residue:
641
Sequence:
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQEGGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
  
Inhibitor
Name:
BDBM57703
Synonyms:
MLS000394802 | N-[(Z)-(1-methyl-2-oxidanylidene-indol-3-ylidene)amino]-2-thiophen-2-yl-quinoline-4-carboxamide | N-[(Z)-(1-methyl-2-oxo-3-indolylidene)amino]-2-thiophen-2-yl-4-quinolinecarboxamide | N-[(Z)-(1-methyl-2-oxoindol-3-ylidene)amino]-2-thiophen-2-ylquinoline-4-carboxamide | N-[(Z)-(2-keto-1-methyl-indolin-3-ylidene)amino]-2-(2-thienyl)cinchoninamide | SMR000242891 | cid_6901801
Type:
Small organic molecule
Emp. Form.:
C23H16N4O2S
Mol. Mass.:
412.464
SMILES:
CN1C(=O)\C(=N/NC(=O)c2cc(nc3ccccc23)-c2cccs2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: