Reaction Details Report a problem with these data
Target
Epstein-Barr nuclear antigen 1
Ligand
BDBM62502
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
IC50
7181±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay (2010)[AID] 
Target
Name:
Epstein-Barr nuclear antigen 1
Synonyms:
EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56444.81
Organism:
Human herpesvirus 4
Description:
gi_23893623
Residue:
641
Sequence:
MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQEGGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
  
Inhibitor
Name:
BDBM62502
Synonyms:
2-[2-(Benzo[1,3]dioxol-5-yloxy)-acetylamino]-4-methyl-thiazole-5-carboxylic acid ethyl ester | 2-[[2-(1,3-benzodioxol-5-yloxy)-1-oxoethyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester | 2-[[2-(1,3-benzodioxol-5-yloxy)acetyl]amino]-4-methyl-thiazole-5-carboxylic acid ethyl ester | MLS001222226 | SMR000605882 | cid_6493294 | ethyl 2-[2-(1,3-benzodioxol-5-yloxy)ethanoylamino]-4-methyl-1,3-thiazole-5-carboxylate | ethyl 2-[[2-(1,3-benzodioxol-5-yloxy)acetyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H16N2O6S
Mol. Mass.:
364.373
SMILES:
CCOC(=O)c1sc(NC(=O)COc2ccc3OCOc3c2)nc1C
Structure:
Search PDB for entries with ligand similarity: