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Target
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Ligand
BDBM64799
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1)
IC50
52346±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Synonyms:
PP-1A | PP1A_HUMAN | PPP1A | PPP1CA | Serine/threonine protein phosphatase PP1-alpha catalytic subunit | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | protein phosphatase 1, catalytic subunit, alpha isoform 3
Type:
PROTEIN
Mol. Mass.:
37510.66
Organism:
Homo sapiens (Human)
Description:
ChEMBL_197827
Residue:
330
Sequence:
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
  
Inhibitor
Name:
BDBM64799
Synonyms:
(4aS)-2,4a,9-trimethyl-2,3,4,4a,9,9a-hexahydro-[1,2]oxazino[6,5-b]indol-6-ol | (4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-[1,2]oxazino[6,5-b]indol-6-ol | (4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazin[6,5-b]indol-6-ol | (4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazino[6,5-b]indol-6-ol | MLS001060820 | SMR000486281 | cid_24747147
Type:
Small organic molecule
Emp. Form.:
C13H18N2O2
Mol. Mass.:
234.2942
SMILES:
CN1C2ON(C)CC[C@@]2(C)c2cc(O)ccc12
Structure:
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