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Target
NADPH oxidase 1
Ligand
BDBM65840
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify inhibitors of NOX1: HEK/293 IC50
IC50
360±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify inhibitors of NOX1: HEK/293 IC50 PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM65840
Synonyms:
6,11-dihydroquinoxalino[2,3-b]quinoxaline | ML090 | SR-01000634517 | SR-01000634517-1 | cid_616479
Type:
Small organic molecule
Emp. Form.:
C14H10N4
Mol. Mass.:
234.256
SMILES:
N1c2ccccc2Nc2nc3ccccc3nc12
Structure:
Search PDB for entries with ligand similarity: