Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM42513
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
4057±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM42513
Synonyms:
(E)-1-(1H-benzimidazol-2-yl)-3-(3-chlorophenyl)-2-propen-1-one | (E)-1-(1H-benzimidazol-2-yl)-3-(3-chlorophenyl)prop-2-en-1-one | MLS000543517 | SMR000163981 | cid_8178372
Type:
Small organic molecule
Emp. Form.:
C16H11ClN2O
Mol. Mass.:
282.724
SMILES:
Clc1cccc(\C=C\C(=O)c2nc3ccccc3[nH]2)c1
Structure:
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