Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM65993
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
5356±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM65993
Synonyms:
2-[1-[(E)-2-nitrovinyl]-2-naphthoxy]acetic acid ethyl ester | 2-[[1-[(E)-2-nitroethenyl]-2-naphthalenyl]oxy]acetic acid ethyl ester | MLS000584937 | SMR000207322 | cid_684448 | ethyl ({1-[(E)-2-nitrovinyl]-2-naphthyl}oxy)acetate | ethyl 2-[1-[(E)-2-nitroethenyl]naphthalen-2-yl]oxyacetate | ethyl 2-[1-[(E)-2-nitroethenyl]naphthalen-2-yl]oxyethanoate
Type:
Small organic molecule
Emp. Form.:
C16H15NO5
Mol. Mass.:
301.294
SMILES:
CCOC(=O)COc1ccc2ccccc2c1\C=C\[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: