Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66004
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
7439±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66004
Synonyms:
1-ethyl-N-(2-ethyl-4-keto-quinazolin-3-yl)-2-hydroxy-4-keto-quinoline-3-carboxamide | 1-ethyl-N-(2-ethyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanyl-4-oxidanylidene-quinoline-3-carboxamide | 1-ethyl-N-(2-ethyl-4-oxo-3-quinazolinyl)-2-hydroxy-4-oxo-3-quinolinecarboxamide | 1-ethyl-N-(2-ethyl-4-oxoquinazolin-3-yl)-2-hydroxy-4-oxoquinoline-3-carboxamide | MLS000765044 | SMR000283049 | cid_983222
Type:
Small organic molecule
Emp. Form.:
C22H20N4O4
Mol. Mass.:
404.4186
SMILES:
CCc1nc2ccccc2c(=O)n1NC(=O)c1c(O)c2ccccc2n(CC)c1=O
Structure:
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