Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66005
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
1111±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66005
Synonyms:
3-(1,3-benzoxazol-2-yl)-8-methoxy-1-benzopyran-2-one | 3-(1,3-benzoxazol-2-yl)-8-methoxy-2H-chromen-2-one | 3-(1,3-benzoxazol-2-yl)-8-methoxy-chromen-2-one | 3-(1,3-benzoxazol-2-yl)-8-methoxy-coumarin | 3-(1,3-benzoxazol-2-yl)-8-methoxychromen-2-one | MLS000723832 | SMR000305427 | cid_626179
Type:
Small organic molecule
Emp. Form.:
C17H11NO4
Mol. Mass.:
293.2735
SMILES:
COc1cccc2cc(-c3nc4ccccc4o3)c(=O)oc12
Structure:
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