Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66006
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
5662±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66006
Synonyms:
(5Z)-1-(4-ethoxyphenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-diazinane-4,6-dione | (5Z)-1-(4-ethoxyphenyl)-5-(thien-2-ylmethylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | (5Z)-1-p-phenetyl-5-(2-thenylidene)-2-thioxo-hexahydropyrimidine-4,6-quinone | MLS000724090 | SMR000305685 | cid_2226076
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3S2
Mol. Mass.:
358.435
SMILES:
CCOc1ccc(cc1)N1C(=S)NC(=O)C(=Cc2cccs2)C1=O |w:16.17|
Structure:
Search PDB for entries with ligand similarity: