Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM66141
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase
IC50
>59640±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29494.42
Organism:
Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Description:
gi_60115532
Residue:
269
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDGESGNYG
  
Inhibitor
Name:
BDBM66141
Synonyms:
5-Nitro-furan-2-carboxylic acid [2-(2-fluoro-phenyl)-benzooxazol-5-yl]-amide | MLS001194759 | N-[2-(2-fluorophenyl)-1,3-benzoxazol-5-yl]-5-nitro-2-furamide | N-[2-(2-fluorophenyl)-1,3-benzoxazol-5-yl]-5-nitro-2-furancarboxamide | N-[2-(2-fluorophenyl)-1,3-benzoxazol-5-yl]-5-nitro-furan-2-carboxamide | N-[2-(2-fluorophenyl)-1,3-benzoxazol-5-yl]-5-nitrofuran-2-carboxamide | SMR000554884 | cid_3116398
Type:
Small organic molecule
Emp. Form.:
C18H10FN3O5
Mol. Mass.:
367.2875
SMILES:
[O-][N+](=O)c1ccc(o1)C(=O)Nc1ccc2oc(nc2c1)-c1ccccc1F
Structure:
Search PDB for entries with ligand similarity: