Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM66123
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase
IC50
16060±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase PubChem Bioassay (2010)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | metallo-beta-lactamase IMP-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27125.88
Organism:
Pseudomonas aeruginosa
Description:
gi_27368096
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM66123
Synonyms:
9-aminopyrido[1,2-a]quinolinium | 9-benzo[c]quinolizin-11-iumamine;perchlorate | MLS001180155 | SMR000477592 | benzo[c]quinolizin-11-ium-9-amine;perchlorate | benzo[c]quinolizin-11-ium-9-ylamine;perchlorate | cid_23723895
Type:
Small organic molecule
Emp. Form.:
C13H11N2
Mol. Mass.:
195.2393
SMILES:
Nc1ccc2ccc3cccc[n+]3c2c1
Structure:
Search PDB for entries with ligand similarity: