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Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM66188
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
IC50
1001±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM66188
Synonyms:
6-bromanyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid | 6-bromo-2-methyl-4-phenyl-3-quinolinecarboxylic acid | 6-bromo-2-methyl-4-phenyl-quinoline-3-carboxylic acid | 6-bromo-2-methyl-4-phenylquinoline-3-carboxylic acid | MLS001173402 | SMR000538992 | cid_757946
Type:
Small organic molecule
Emp. Form.:
C17H12BrNO2
Mol. Mass.:
342.187
SMILES:
Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(O)=O
Structure:
Search PDB for entries with ligand similarity: