Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66570
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66570
Synonyms:
3,4,5-trimethoxy-N-[(2-methyl-4-quinolinyl)methyl]benzamide | 3,4,5-trimethoxy-N-[(2-methyl-4-quinolyl)methyl]benzamide | 3,4,5-trimethoxy-N-[(2-methylquinolin-4-yl)methyl]benzamide | MLS000728974 | SMR000307252 | cid_1503107
Type:
Small organic molecule
Emp. Form.:
C21H22N2O4
Mol. Mass.:
366.4104
SMILES:
COc1cc(cc(OC)c1OC)C(=O)NCc1cc(C)nc2ccccc12
Structure:
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