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Target
Bcl-2-like protein 11
Ligand
BDBM66960
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66960
Synonyms:
2-(2-furoylamino)acetic acid [2-[benzyl(tert-butyl)amino]-2-keto-ethyl] ester | 2-[[2-furanyl(oxo)methyl]amino]acetic acid [2-[tert-butyl-(phenylmethyl)amino]-2-oxoethyl] ester | MLS001138725 | SMR000714635 | [2-[benzyl(tert-butyl)amino]-2-oxoethyl] 2-(furan-2-carbonylamino)acetate | [2-[tert-butyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl] 2-(furan-2-ylcarbonylamino)ethanoate | cid_24980209
Type:
Small organic molecule
Emp. Form.:
C20H24N2O5
Mol. Mass.:
372.415
SMILES:
CC(C)(C)N(Cc1ccccc1)C(=O)COC(=O)CNC(=O)c1ccco1
Structure:
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