Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67104
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67104
Synonyms:
3-(4-fluorophenyl)-4-keto-phthalazine-1-carboxylic acid | 3-(4-fluorophenyl)-4-oxidanylidene-phthalazine-1-carboxylic acid | 3-(4-fluorophenyl)-4-oxo-1-phthalazinecarboxylic acid | 3-(4-fluorophenyl)-4-oxophthalazine-1-carboxylic acid | SR-03000000773-1 | cid_1485877
Type:
Small organic molecule
Emp. Form.:
C15H9FN2O3
Mol. Mass.:
284.242
SMILES:
OC(=O)c1nn(-c2ccc(F)cc2)c(=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: