Reaction Details
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Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67119
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] More Info.:
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
Inhibitor
Name:
BDBM67119
Synonyms:
2-(4-indan-5-ylsulfonylpiperazino)-N-phenyl-butyramide | 2-[4-(2,3-dihydro-1H-inden-5-ylsulfonyl)-1-piperazinyl]-N-phenylbutanamide | 2-[4-(2,3-dihydro-1H-inden-5-ylsulfonyl)piperazin-1-yl]-N-phenyl-butanamide | 2-[4-(2,3-dihydro-1H-inden-5-ylsulfonyl)piperazin-1-yl]-N-phenylbutanamide | SR-03000000788-1 | cid_17498738
Type:
Small organic molecule
Emp. Form.:
C23H29N3O3S
Mol. Mass.:
427.56
SMILES:
CCC(N1CCN(CC1)S(=O)(=O)c1ccc2CCCc2c1)C(=O)Nc1ccccc1
Structure:
