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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67131
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67131
Synonyms:
4-keto-3-phenyl-phthalazine-1-carboxylic acid cyclohexylmethyl ester | 4-oxo-3-phenyl-1-phthalazinecarboxylic acid cyclohexylmethyl ester | SR-03000000857-1 | cid_7184758 | cyclohexylmethyl 4-oxidanylidene-3-phenyl-phthalazine-1-carboxylate | cyclohexylmethyl 4-oxo-3-phenylphthalazine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C22H22N2O3
Mol. Mass.:
362.4217
SMILES:
O=C(OCC1CCCCC1)c1nn(-c2ccccc2)c(=O)c2ccccc12
Structure:
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